ATR ATM

Natural killer cells: DNA damage link to innate immunity - Cell Signaling Update - Signaling Gateway: "DNA damage alerts cells of the immune system to attack damaged self cells, and it is possible that this mechanism also operates to trigger immune responses to virally infected cells. It remains to be established whether this mechanism can account for at least some of the effects of chemotherapy and radiation therapy, but the signalling pathway that involves ATR and/or ATM could become a target for the development of new therapeutics for cancer."