2005/11/17

Ku86 Genetic Switch Involved In Cells' DNA topoisomerase I Response To Radiation Therapy

Researchers Discover Genetic Switch Involved In Cells' Response To Radiation Therapy: "The investigation focused on an enzyme called DNA topoisomerase I, which is responsible for cutting single DNA strands so that the DNA molecule can rotate and unwind during transcription and replication. Camptothecin stops DNA topoisomerase I during the unwinding process, ultimately killing the cell."

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