YidC1 YidC2

Bacteria That Cause Tooth Decay Able To Survive Without Important Biochemical Pathway: "Brady's team surmised that two other molecules, called YidC1 and YidC2, might be acting as alternate routes for protein delivery in the absence of the SRP pathway. They tested their hypothesis and found that S. mutans could continue to function in non-stress conditions without the SRP and YidC1 genes, but not without the YidC2 and SRP simultaneously.
'The fact that the bacteria could survive without the SRP pathway was the most striking finding for scientists in the membrane protein insertion field,' said Ross E. Dalbey, Ph.D., a professor of chemistry at The Ohio State University. 'The big question now is discovering how these proteins are targeted in the absence of the SRP pathway, and I think that will be an important area of future research.' "